OPHTOVIR JUST TEARS - Carboxymethylcellulose Sodium 0.5% Eye Drops

Composition  

Acyclovir        USP 3% w/w

Sterile Paraffin Base   q.s

Dosage form

Ophthalmic Ointment

Category

Antibiotic + Steroid

Dosage form

Eye ointment

Description

Acyclovir is an antiviral agent which is highly active in vitro against herpes simplex (HSV) types I and II, but its toxicity to mammalian cells is low.

Acyclovir is phosphorylated to the active compound acyclovir triphosphate after entry into herpes infected cell. The first step in this process requires the presence of the HSV coded thymidine kinase. Acyclovir triphosphate acts as an inhibitor of, and substrate for, herpes specified DNA polymerase, preventing further viral DNA synthesis without affecting normal cellular processes.

Dosage

I cm ribbon of ointment should be placed inside the lower conjunctival sac five times a day at approximately four hourly intervals, omitting the night time application. Treatment should continue for at least 3 days after healing is complete.

Contraindications

Hypersensitivity to any components of this medication.

Warnings & Precautions

Pregnancy

The use of Acyclovir ophthalmic ointment should be considered only when the potential benefits outweigh the possibility of unknown risk.

Lactating Women

The use of Acyclovir ophthalmic ointment should be considered only when the potential benefits outweigh the possibility of unknown risk to a lactating woman.

Pediatric Use

Safety and effectiveness in pediatric patients have not been established

Adverse Effects

Transient mild stinging immediately following application may occur in a small proportion of patients.

Superficial punctate keratopathy has been reported but has not resulted in patients being withdrawn from therapy and healing has occurred without apparent sequelae. Local irritation and inflammation such as blepharitis and conjunctivitis have also been reported

Storage

Store in a cool dry place. Protect from light.

Presentation

OPHTHOVIR Eye Drop is available in sterile Tube of 5 g