PARACAINE - Proparacaine 0.5% Ophthalmic Solution

Composition  

Proparacaine Hydrochloride   U.S.P. 0.5%

Chlorbutol (as preservative)    I.P 0.5%

Aqueous Base q.s.

Dosage form

Ophthalmic Solution (Eye Drops)

Description

Proparacaine hydrochloride ophthalmic solution is a rapidly acting topical anesthetic, with induced anesthesia lasting approximately 10-20 minutes.

Indications

Proparacaine hydrochloride ophthalmic solution is indicated for procedures in which a topical ophthalmic anesthetic is indicated: corneal anesthesia of short duration, e.g., tonometry, gonioscopy, removal of corneal foreign bodies, and for short corneal and conjunctival procedures.

Dosage

Removal of foreign bodies and sutures, and for tonometry: 1 to 2 drops (in single instillations) in each eye before operating.

Short corneal and conjunctival procedures : 1 drop in each eye every 5 to 10 minutes for 5-7 doses.

Contraindications

Proparacaine hydrochloride ophthalmic solution should be considered contraindicated in patients with Known hypersensitivity to any of the ingredients of this preparation.

Warnings

Prolonged use of a topical ocular anesthetic is not recommended. It may produce permanent corneal opacification with accompanying visual loss.

Pregnancy

Proparacaine hydrochloride should be administered to a pregnant woman only if clearly needed.

Adverse Effects

Occasional temporary stinging, burning, and conjunctival redness may occur with the use of proparacaine. A rare, severe, immediate-type, apparently hyperallergic corneal reaction, characterized by acute, intense and diffuse epithelial keratitis, a gray, ground glass appearance, sloughing of large areas of necrotic epithelium, corneal filaments and sometimes, iritis with descemetitis has been reported.

Storage

Store in a cool dry place. Protect from light.

Presentation

PARACAINE Eye Drops is available in sterile plastic bottle of 5 ml.